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Tagpo, Ardisia elliptica, SHOEBUTTON ARDISIA - Philippine Herbal Medicine - An illustrated compilation of Philippine medicinal plants by Dr Godofredo Stuart with botanical information, chemical properties, folkloric uses and medicinal research studies.
The anti-platelet effects of the isolates were evaluated by suppressing collagen- and AA-induced platelet aggregation in washed rabbit platelets. The results of anti-platelet aggregation experiments indicate that compounds 1, 3, 5, 7, 8, and the mixture of 12 and 13 can significantly inhibit collagen- and/or AA-induced platelet aggregation at ...
New ent-kaurane diterpenoids with anti-platelet aggregation activity from Annona squamosa J Nat Prod. 2002 Oct;65 (10):1462-7 ... Compound 1 is the first dimeric ent-kaurane derivative to have been reported from a plant in the family Annonaceae. Certain useful NMR data were generalized to determine the stereochemistry of C-16 among the ent ...
Amides with anti-platelet aggregation activity from Piper taiwanense Fitoterapia. 2007 Sep;78(6):414-9. doi: 10.1016/j.fitote.2007.04.009. Epub 2007 May 24. Authors Ih-Sheng Chen 1, Yu-Chang Chen, Chang-Hui Liao. Affiliation 1 Graduate Institute of ... Plant Extracts / administration & dosage
Three anthraquinone glycosides were found to be platelet anti-aggregatory constituents of seeds of Cassia obtusifolia and their structure-activity relationships are discussed. Three anthraquinone glycosides, gluco-obtusifolin [11], gluco-chryso-obtusin [15], and gluco-aurantioobtusin [13], were found to be platelet anti-aggregatory constituents of seeds of …
Stago's platelet aggregometer can be used in the: Diagnosis of Platelet function disorders; Confirmation of HIT; Monitoring of anti-platelet drugs; Identification of Von Willibrand Disease via Ristocetin Induced Platelet Aggregation (RIPA) Stago offers six reagents for use on the TA Series aggregometer: Arachidonic Acid (Ref:86922) ADP (Ref: 86923)
Ginger is the rhizome of Zingiber officinale, a perennial plant in the family Zingiberaceae. It is consumed as delicacy, medicine, or spice. It is often pickled in vinegar or sherry as a snack or just cooked as an ingredient in many dishes. ... The anti-platelet aggregation results are summarized in Table 1. All the tested compounds displayed ...
Anti-platelet agents are those that decrease platelet aggregation and inhibit thrombus formation. Anti-platelet drugs are used to prevent and help in the reversal of platelet aggregation in arterial thrombosis which is the principal reason in the pathology of myocardial infarction (MI) and ischemic stroke.
Results: Of the main plants discussed in this review, which have antiplatelet activity, some include saffron, garlic, green tea, St. John's wort, ginger, ginkgo biloba, ginseng, and …
The anti-platelet aggregation effects of the two medicines induced by arachidonic acid (AA) were investigated. Results: The chemical profiles of these two species of "Dragon's Blood" were significantly different. The characteristic constituents were found to be: flavanes in RDD and stilbenes in RDC. ... Plant Extracts / pharmacology*
Two new (1-2) and six known (3-8) nucleoside alkaloids were isolated from the rhizomes of Ligusticum striatum DCpounds 1 and 2 (liguadenosines A and B) were unusual N-10 substituted adenosine derivatives. Their structures were elucidated by extensive spectroscopic analyses and ECD calculation. Most of them significantly inhibited the abnormal increase in …
The inhibitory activities of I and II against rat platelet aggregation were compared with that of aspirin, a known inhibitor of platelet aggregation. Discussions also included the results of the investigations on the structural activity relationships among the various dihydroxybenzoic acid derivatives against platelet aggregations induced by ...
Anti-platelet aggregation constituents from Gynura elliptica Phytochemistry. 2000 Apr;53(8):833-6. doi: 10.1016/s0031-9422(99)00599-3. Authors W Y Lin 1, C M Teng, I L Tsai, I S Chen. Affiliation 1 Graduate Institute of Pharmaceutical ... Plant Oils / chemistry
Anti-platelet aggregation and chemical constituents from the rhizome of Gynura japonica Planta Med. 2003 Aug;69(8):757-64. doi: 10.1055/s-2003-42796. Authors Wei-Yu Lin 1 ... Plant Oils / pharmacology* Plant Oils / therapeutic use Platelet Aggregation / drug effects* ...
tropical country with plenty of medicinal plants, from which a potential drug for anti-thrombolytic activities can be prepared. Therefore, an overview of Vietnamese medicinal plants with anti-platelet aggregation activities, such as Panax L., Canna, is highly needed for improving the quality of exploiting Vietnamese medicinal resources.
Consumption of plant-food-derived bioactives, particularly flavonoids, has shown antithrombotic, and cardiovascular protective effects due to its anti-platelet activity. Preclinical and clinical trials have proven that flavonoid-rich plant extracts are protective against the cardiac ailments through anti-platelet aggregation activity.
Background: Platelet aggregation is a crucial mechanism in the progression of atherothrombotic events. This systematic review aims to introduce the plants studied in healthy people as the primary ...
Anti-thrombotic Effects Mediated by a Novel Dual-Target Peptide Inhibiting Both Platelet Aggregation and Thrombin Activity without Causing Bleeding ... but only PTIP was capable of inhibiting platelet aggregation. PTIP (1.0 mg/kg) decelerated thrombosis formation in venous and arterial vessels induced by FeCl3 injury. PTIP (1.0 mg/kg) also ...
Quercetin and its derivatives (isorhamnetin and tamarixetin) exert potent antithrombotic activity and effects on platelet inhibition demonstrated through the suppression of platelet …
The ADP (P2Y 12 as the most important receptor) induced abnormal platelet aggregation that lead to thrombus could initiate a greater risk of cardiovascular diseases (Gao et al., 2014; Song et al., 2021; Yang et al., 2019), and literature showed some rare ginsenosides (Rk1, Rh2, PPD) that produced by steaming exhibited apparent anti-platelet ...
Many anti-thrombosis and anti-platelet aggregation drugs have been discovered and applied in treatment. However, these drugs have many side effects such as bleeding, stomach lesion, etc. Vietnam is a tropical country with plenty of medicinal plants, from which a potential drug for anti-thrombolytic activities can be prepared. ... Therefore, an ...
↓ Platelet aggregation (healthy donors); ↓ platelet aggregation (donors with cardiovascular disorders); no cytotoxicity effects on human blood platelets, mouse fibroblast cultures L929 and human lung cells A549 : A. ursinum and A. sativum extracts: Blood from healthy volunteers: ↓ Platelet aggregation via inhibition ADP pathway
Handbook of compounds with anti-inflammatory and anti-platelet aggregation activities isolated from plants ... Handbooks, Platelet Aggregation Inhibitors -- Handbooks, Plant Extracts -- isolation & purification -- Handbooks, Plants, Medicinal -- metabolism -- Handbooks ...
Platelet aggregation inhibitors work in different places of the clotting cascade and prevent platelet adhesion, therefore no clot formation. Aspirin, the most commonly used antiplatelet drug changes the balance between prostacyclin (which inhibits platelet aggregation) and thromboxane (that promotes aggregation). ...
Although some compounds isolated from this plant have anti-platelet aggregation effects, the main chemical components and mechanism of J. procumbens in terms of these effects are little known. Aims of the study: Through in vivo and in vitro experiments, this studsy revealed the characteristic components and action mechanism of anti-platelet ...
Many anti-thrombosis and anti-platelet aggregation drugs have been discovered and applied in treatment. However, these drugs have many side effects such as bleeding, stomach lesion, etc. Vietnam ...
Osunsanmi, F. O., Oyinloye, B. E., Mosa, R. A., Ikhile, M. I., Ngila, J. C., Shode, F. O., … Opoku, A. R. (2016). Anti-platelet aggregation of mixtures of betulinic ...
It was postulated that both plants may contain common active constituents that contribute to inhibiting blood coagulation and/or platelet aggregation. Eighteen compounds, which have …
ABSTRACT Rapanea melanophloeos (L.) Mez is a medicinal plant that is used by Zulu traditional healers to manage blood-clot related diseases.Various extracts (methanol, n- hexane, chloroform, ethyl acetate and water) prepared from the bark of R. melanophloeos were screened for phytochemicals, antioxidant, and anti-platelet ...
Bioassay-directed fractionation of an ethanolic extract of the galls of Sapindus mukorossi has resulted in the isolation of two new tirucallane-type triterpenoid saponins, sapinmusaponins Q (1) and R (2), along with three known oleanane-type triterpenoid saponins (3-5). Their structures were elucida …